Melalumin® Ultra
Depigmenting Cream

20 g

Melalumin® Ulta Depigmenting Cream’s scientific formula actively acts on all stages of your melanin cycle to reduce hyperpigmentation. The cream exfoliates, lightens, moisturizes, and protects your skin to promote healthy and glowing skin. With a multifaceted approach, it nourishes your skin with essential nutrients, leaving behind even-toned, healthy-looking skin.

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Key Ingredients:

Key Ingredients:

Benefits

  • 1aLightens your skin 1
  • Promotes skin regeneration 3
  • Repairs damaged skin 5
  • 2 Fights age spots and freckles1b
  • 4 Protects against radical damage
  • 6 Deep moisturization3b
  • 8 1 Lightens your skin
  • 10 2Fights age spots and freckles
  • 12 3Promotes skin regeneration
  • 14 4Protects against radical damage
  • 16 5Repairs damaged skin
  • 18 6Deep moisturization

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Frequently Asked Questions

Melalumin® Ultra, Depigmenting & Skin Lightening Cream has effective action at all the stages of the Melanin cycle to naturally manage skin pigmentation. It comprises effective melanin suppressors, exfoliators, and unique skin ingredients to provide nourishment that makes skin healthy & luminous.

No, the Melalumin® Ultra Depigmenting Cream contains no steroids.

The Melalumin® Ultra Depigmenting Cream should be applied twice daily or as directed by the physician.

The Melalumin® Ultra Depigmenting Cream requires no weaning-off. Its use can be stopped immediately if required.

Yes, Melalumin® Ultra Depigmenting Cream can be used in winter. It is suitable for use in all seasons.

References:


1. Mondal P, Bhalla V, Tyagi R. A comprehensive review on a skin-brightening agent kojic acid and its applications. J Popul Ther Clin Pharmacol. 2024;31(5):399-409. doi:10.53555/jptcp.v31i5.6165

(Reference Text a: KA is designated as a skin lightening agent that acts during the actual synthesis of melanin, exhibiting a sufficient inhibitory effect on monophenolase activity.)

(Reference Text b: KA is showing great promise in combating the appearance of skin aging and wrinkling)

2. Boo YC. Arbutin as a skin depigmenting agent with antimelanogenic and antioxidant properties. Antioxidants (Basel). 2021;10(7):1129. doi:10.3390/antiox10071129

(Reference Text a: Arbutin attenuated the hydroxyl radical generation in both reactions, suggesting that arbutin can reduce the levels of ROS derived from the melanogenic pathway. Arbutin at 500 uM was also shown to reduce intracellular hydroxyl radical production. Thus, arbutin and α-arbutin may reduce ROS levels by directly scavenging free radicals or indirectly enhancing the antioxidant capacity of cells through the activation of the Nrf2-ARE pathway. These antioxidant properties may contribute to the inhibitory action of arbutin and α-arbutin on melanin synthesis in cells.)

3. Boo YC. Mechanistic basis and clinical evidence for the applications of nicotinamide (niacinamide) to control skin aging and pigmentation. Antioxidants (Basel). 2021;10(8):1315. doi:10.3390/antiox10081315

(Reference Text a: The progression of skin aging and hyperpigmentation in clinical trials. These studies suggest that the topical application of nicotinamide may alleviate oxidative stress and reduce cytotoxicity, inflammation, and pigmentation in the skin. Anti-Inflammatory Effects of Nicotinamide)

(Reference Text b: Improvement effects on skin moisture, skin barrier, elasticity, surface morphology, skin clarity, and/or pigmentation)

4. Quan T. Human skin aging and the anti-aging properties of retinol. Biomolecules. 2023;13(11):1614. doi:10.3390/biom13111614

(Reference Text: Topical ROL to aged human skin in a live setting has been found to significantly enhance the thickness of the epidermis by stimulating the proliferation of epidermal keratinocytes. These findings suggest that topical ROL enhances the activity of the epidermal-specific c-Jun transcription factor, thereby stimulating the proliferation of epidermal keratinocytes in aged human skin in vivo. The mechanisms by which retinoic acid improves hyperpigmentation include the following: the acceleration of cellular turnover: by promoting skin cell turnover, retinoic acid helps to exfoliate pigmented cells, revealing fresh, less-pigmented skin beneath; collagen stimulation: retinoic acid can improve skin texture.)

5. Babilas P, Knie U, Abels C. Cosmetic and dermatologic use of alpha hydroxy acids. J Dtsch Dermatol Ges. 2012;10(7):488-91. doi:10.1111/j.1610-0387.2012.07939.x

(Reference Text: Besides their use for skin rejuvenation, AHA peelings can also be applied to remove epidermal skin alterations. Newman and coworkers investigated the histological and clinical effects of glycolic acid (50%) on photoaged skin.)

6. Data on file. Substantiation of Actives for Melalumin Ultra. Sami Labs Limited 2017.