Melalumin®
Depigmenting Cream

15 g

Melalumin® Depigmenting Cream is specially formulated to work on all melanin cycle stages effectively. The cream lightens, hydrates, protects and exfoliates your skin to encourage healthy, beautiful skin. It uses a comprehensive strategy to provide your skin with essential nutrients, resulting in skin that is even-toned and appears healthy.

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Key Ingredients:

Key Ingredients:

Benefits

  • 1 Promotes skin-cell regeneration 1
  • 2 Balances moisture 3
  • 5 Controls melanin production 5
  • 2 2,3,5 Fights hyperpigmentation
  • 4 1 Even tones your skin
  • 6 6 Boosts skin repair
  • 8 1 Promotes skin-cell regeneration
  • 10 2Fights hyperpigmentation
  • 12 3 Balances moisture
  • 14 4Even tones your skin
  • 16 5 Controls melanin production
  • 18 6Boosts skin repair

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Frequently Asked Questions

Melalumin® Depigmenting Cream is a mixture of melanin suppressors and UV protectants that helps to maintain even skin tone and minimize pigmentation problems naturally. It also has unique ingredients like CosmeVit DCx that provides nourishment leaving skin healthy and luminous.

No, the Melalumin® Depigmenting Cream contains no steroids.

The Melalumin® Depigmenting Cream should be applied twice daily or as directed by the physician.

The Melalumin® Depigmenting Cream requires no weaning-off. Its use can be stopped immediately if required.

Yes, Melalumin® Depigmenting Cream can be used in winter. It is suitable for use in all seasons.

References:

1. Babilas P, Knie U, Abels C. Cosmetic and dermatologic use of alpha hydroxy acids. J Dtsch Dermatol Ges. 2012;10(7):488-491. doi:10.1111/j.1610-0387.2012.07939.x

(Reference Text: The simplest AHA is the glycolic acid (alpha hydroxy acetic acid). The most commonly used substance for peeling in Germany is glycolic acid. Besides their use for skin rejuvenation, AHA peelings can also be applied to remove epidermal skin alterations like seborrheic or actinic keratoses as well as senile lentigines and verrucae vulgares and to improve xerosis, striae distensae, reticulated papillomatosis, psoriasis and verrucae planae.)

2. Boo YC. Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation. Antioxidants (Basel). 2021;10(8):1315. Published 2021 Aug 21. doi:10.3390/antiox10081315

(Reference Text: Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials. Combination of kinetin and nicotinamide reduced pore, wrinkle, unevenness, erythema, and spot at weeks 8 and 12 and increased corneal moisture at week 12)

3. Prantika Mondal et al. A COMPREHENSIVE REVIEW ON A SKIN-BRIGHTENING AGENT KOJIC ACID AND ITS APPLICATIONS, Vol.31 No.5 (2024): JPTCP (399-409)

(Reference Text: KA is designated as a skin lightening agent that acts during the actual synthesis of melanin, exhibiting a sufficient inhibitory effect on monophenolase activity. KA is showing great promise in combating the appearance of skin aging and wrinkling.)

4. Boo YC. Arbutin as a Skin Depigmenting Agent with Antimelanogenic and Antioxidant Properties. Antioxidants (Basel). 2021;10(7):1129. Published 2021 Jul 15. doi:10.3390/antiox10071129

(Reference Text: Arbutin attenuated the hydroxyl radical generation in both reactions, suggesting that arbutin can reduce the levels of ROS derived from the melanogenic pathway. Arbutin at 500 μM was also shown to reduce intracellular hydroxyl radical production. Thus, arbutin and α-arbutin may reduce ROS levels by directly scavenging free radicals or indirectly enhancing the antioxidant capacity of cells through the activation of the Nrf2-ARE pathway. These antioxidant properties may contribute to the inhibitory action of arbutin and α-arbutin on melanin synthesis in cells.)

5. Data on file. Substantiation of Actives for Melalumin Ultra. Sami Labs Limited 2017.

6. Quan T. Human Skin Aging and the Anti-Aging Properties of Retinol. Biomolecules. 2023;13(11):1614. Published 2023 Nov 4. doi:10.3390/biom13111614

(Reference Text: Topical ROL to aged human skin in a live setting has been found to significantly enhance the thickness of the epidermis by stimulating the proliferation of epidermal keratinocytes. This occurs through the stimulation of the growth of epidermal keratinocytes and dermal endothelial cells in the context of aging human skin in vivo. These findings suggest that topical ROL enhances the activity of the epidermal-specific c-Jun transcription factor, thereby stimulating the proliferation of epidermal keratinocytes in aged human skin)